| 1. | Then they seem to acquire immunity , ” he explains 然后,他们似乎就产生了免疫力。
|
| 2. | Thus , the complement system act as a link between innate and acquired immunity 因此,补体是连接机体天然免疫和获得性免疫( adaptiveimmunity )的“桥梁” 。
|
| 3. | Vaccination with dtwp opv can be continued with dtap - ipv and this transition is both safe and effective in acquiring immunity for your child 以新疫苗dtap - ipv代替原有疫苗dtwp opv不但安全,而且能为儿童提供有效的免疫保护。
|
| 4. | Can my baby acquire immunity if he she receives some doses of dtwp opv and some doses of dtap - ipv vaccines ? will there be any adverse effects from such a programme 以新旧两种疫苗dtap - ipv及dtwp opv完成接种能否为幼儿带来有效的保护此接种方法会否引起不良效果
|
| 5. | We hope that our study will provide us with more comprehensive knowledge of the mechanisms of immune regulation and the roles that dc and complement play in innate and acquired immunity , as well as to lay a foundation for further exploration of the roles dc play in antigen - specific immune responses and immune tolerance from a new perspective . part i expression of complement receptors and complement - associated molecules on dendritic cells derived from distinct - origin at different stages of development two subsets of dendritic cells were generated from precursor cells isolated by means of magnetic cell separation system 曰补体受体及其相关分子在modc上的表达不同分化阶段的单核细胞衍生性dc ( monocytes一deriveddc , modc )的诱导:将新鲜分离的单核细胞mo ,在含有gm一csf和工l一4培养体系中诱导5一7d ,即分化为未成熟modc ;对培养至sd的未成熟modc ,用tnfa刺激zd ,即分化为成熟modc ;此时再用lps刺激24h ,即为活化的modc 。
|
| 6. | In view of the common property of dendritic cells and complement , namely their ability to link innate and acquired immunity , and with no reports , to date , addressing the direct effects of complement on the biological functions of dendritic cells , we decided to study the interaction between the complement system and dendritic cells 本研究的完成有助于在免疫应答的调控机制方面获得新的认识,并对补体和dc在连接天然免疫和获得性免疫之间的作用及相互关系能有更全面的理解,为进一步从新的角度和思路深入研究dc在抗原特异性免疫应答与免疫耐受中的作用及其机制奠定基础。
|
| 7. | Dendritic cells are characterized by their ability to efficiently present antigen , and are uniquely equipped to stimulate naive t cell responses . immature dendritic cells acquire antigens from throughout the peripheral body , then migrate to t - lymphocyte - dependent areas of lymph nodes . thus , dendritic cells act as bridges , operating at the interface of innate and acquired immunity 作为机体免疫系统中功能最强的专职性抗原提呈细胞( antigen - presentingcells , apc ) ,树突状细胞( dendriticcells , dc )能高效地摄取、加工处理和提呈抗原,具有较强的迁移能力,并能显著地激活初始型t细胞以启动t细胞免疫应答反应,此外, dc与b细胞以及nk细胞等也存在着相互作用,可见, dc在连接天然免疫和获得性免疫之间起着非常重要的作用。
|
| 8. | It has been demonstrated that complement activating and cr2 cross - linking on b lymphocytes set up a bridge between innate and acquired immunity . the interaction of c3 and cd21 on b lymphocytes will benefit initiating immune response and regulating primary antibody response . cd21 / cd35 is important in the process of antibody avidity maturing , this is critical to b lymphocyte activation especially in the state of low antigen concentration 现己证实补体的活化以及b细胞表面crz的交联在先天和获得性免疫之间架起了重要的桥梁,表现为c3与b细胞cdzi的相互作用有利于启动抗体应答反应,并对初级抗体应答反应有调节作用: cdzi cd35对于抗体的亲和性成熟具有重要作用,在抗原浓度低的情况下,对于活化b细胞是至关重要的,而且mlgm (交联有利于特异的低亲和性b细胞对t细胞依赖性抗原和t细胞非依赖性抗原产生免疫应答。
|